Regular Exercise Significantly Cuts Colon Cancer Risk





 

A new study confirms that regular exercise significantly decreases colon cancer risk.


 

REGULAR EXERCISE SIGNIFICANTLY CUTS COLON CANCER RISK

As I discuss in my book, A Cancer Prevention Guide for the Human Race, as many as 60 percent of new cancer cases are directly linked to modifiable lifestyle and dietary factors, including many of the worst cancer killers.  Cancers of the gastrointestinal tract, including colon and rectal cancer, have been particularly linked to lifestyle and dietary factors, as I extensively discuss in my book.

A newly published study in the Journal of the National Cancer Institute is an exhaustive meta-analysis study of 21 previously published clinical trials that, in turn, evaluated the link between physical activity levels and colon cancer risk.  As an aside, meta-analysis is commonly used to combine the data from multiple similar clinical research studies, and then analyze that data in such a way that the “statistical power” of the combined meta-analysis study is usually greater than the individual studies that are being evaluated.

When the data from these 21 previously published clinical studies was combined and analyzed, the authors of this new meta-analysis study found that people who regularly engaged in high levels of physical activity were 27 percent less likely to develop cancer in the upper part of the colon when compared to people who were not physically active.  Similarly, highly active people were found to have a 26 percent decrease in the risk of developing cancer in the lower colon when compared to sedentary people.

The link between high levels of physical activity and decreased colorectal cancer risk noted in this meta-analysis is consistent with the research data that I discuss in A Cancer Prevention Guide for the Human Race (as well as other lifestyle and dietary risk factors that are associated with colorectal cancer risk).  A Cancer Prevention Guide for the Human Race is now available in both printed and digital formats from all major bookstores.  Get your copy now, and begin living an evidence-based cancer prevention lifestyle!


Dr. Wascher’s latest video:

Dark as Night, Part 1


Dark as Night, Part 1

Dark as Night, Part 1



At this time, more than 8 percent of Americans are unemployed.  According to the Bureau of Labor Statistics, however, the unemployment rate for veterans who served on active duty between September 2001 and December 2011 is now more than 12 percent.  A new website, Veterans in Healthcare, seeks to connect veterans with potential employers.  If you are a veteran who works in the healthcare field, or if you are an employer who is looking for physicians, advanced practice professionals, nurses, corpsmen/medics, or other healthcare professionals, then please take a look at Veterans in Healthcare. As a retired veteran of the U.S. Army, I would also like to personally urge you to hire a veteran whenever possible.


For a groundbreaking overview of cancer risks, and evidence-based strategies to reduce your risk of developing cancer, order your copy of my bestselling book, “A Cancer Prevention Guide for the Human Race,” from AmazonBarnes & NobleBooks-A-MillionVroman’s Bookstore, and other fine bookstores!

Within one week of publication, A Cancer Prevention Guide for the Human Race was ranked #6 among all cancer-related books on the Amazon.com “Top 100 Bestseller’s List” for Kindle e-books. Within three months of publication, A Cancer Prevention Guide for the Human Race was the #1 book on the Amazon.comTop 100 New Book Releases in Cancer” list.




Disclaimer:  As always, my advice to readers is to seek the advice of your physician before making any significant changes in medications, diet, or level of physical activity


 

Dr. Wascher is an oncologic surgeon, professor of surgery, cancer researcher, oncology consultant, and a widely published author


 

I and the staff of Weekly Health Update would again like to take this opportunity to thank the more than 100,000 health-conscious people from around the world who visit this premier global health information website every month.  (More than 1.3 million pages of high-quality medical research findings were served to the worldwide audience of health-conscious people who visited Weekly Health Update in 2011!)  As always, we enjoy receiving your stimulating feedback and questions, and I will continue to try and personally answer as many of your inquiries as I possibly can.


 



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Multivitamins and Cancer Risk: Reading Between the Lines





 

A new study in the Journal of the American Medical Association claims that a daily multivitamin supplement reduces cancer risk….


 

 

MULTIVITAMINS AND CANCER RISK: READING BETWEEN THE LINES

As I discuss in my book, A Cancer Prevention Guide for the Human Race, recent high-level studies of common vitamins, including antioxidant vitamins, has dimmed the prior enthusiasm that these micronutrients can reduce the risk of cancer, or cardiovascular disease, in otherwise healthy individuals who eat a balanced diet.  Moreover, recent prospective, randomized, placebo-controlled clinical studies have actually suggested that taking supplements of Vitamin E and Vitamin A (including beta-carotene) may actually be harmful to our health, while recent similar studies of Vitamin C supplements have shown neither apparent benefit nor harm.

Despite the almost uniformly discouraging recent research findings regarding most nutritional supplements and their alleged ability to decrease our risk of cancer and other serious illnesses, many people (as well as nutritional supplement manufacturers…) continue to hold out hope that popping a daily vitamin pill, or other nutritional supplement, will protect them from cancer and other dreaded diseases.  (Meanwhile, most people still tend to ignore the evidence-based cancer prevention lifestyle and diet practices that I describe in A Cancer Prevention Guide for the Human Race, and which have been linked, by hundreds of reputable clinical research studies, with a 40 to 60 percent reduction in cancer risk.)  So, it is not surprising to see the extensive and favorable media coverage that is being given to a newly published clinical study looking at the potential impact of daily multivitamin supplements and cancer risk, and which appears in the current issue of the Journal of the American Medical Association.

The Physicians’ Health Study II is a large, ongoing, prospective, randomized, placebo-controlled study of 14,641 male physicians in the United States.  All of these men were at least 50 years of age when they entered into this public health study (the average age of all study participants when they entered into this study was 64 years of age).  This study has observed health outcomes in this very large group of male physicians for an average of 11 years now, and the study’s authors have now reported on the impact of taking a daily commercial multivitamin supplement upon cancer risk and cancer-associated death rates.

To summarize the findings of this very large public health study, the male physicians in this study were secretly randomized to receive either Centrum Silver (a commercial multivitamin and mineral supplement) or a placebo (sugar) pill.  At the time of their entry into this study, 1,312 of these male volunteers were noted to have a prior personal history of cancer.  Following more than 11 years of observation, 2,669 of these physician volunteers were subsequently confirmed to have developed cancer, including 1,373 cases of prostate cancer and 210 cases of colorectal cancer.  When compared with the men who were randomly (and secretly) assigned to the placebo group, the men who were assigned to the multivitamin supplement group experienced an observed, and modest (8 percent), but still significant, reduction in the risk of being diagnosed with cancer.

While this 8 percent reduction in overall cancer risk has been widely trumpeted by other media sites, it is important to note several significant caveats before you run out to the drugstore and buy a case of Centrum Silver.  When one looks at the statistical analysis of the data that resulted in the claimed 8 percent reduction in cancer risk, one immediately notices that the so-called “confidence interval” for this claim extends to 0.998, which is right up against the limit of 1.0 that would render these findings statistically insignificant.  Therefore, the single, sole positive finding in this study of a modest decrease in overall cancer incidence is, itself, at the very borderline of what most statisticians would consider to be a statistically significant finding.

In addition to the single modest (and only barely statistically significant) positive finding of this study, as I have noted above, there was no significant correlation between multivitamin use and the risk of developing prostate cancer, colorectal cancer, or, indeed, any other individual type of cancer.  The absence of any identifiable decrease in the risk of any individual type of cancer in this study, likewise, further calls into question the validity of this study’s single, and statistically borderline, positive finding of an 8 percent reduction in overall cancer incidence among the group of men who were randomized to receive a daily multivitamin tablet.  Moreover, this study also failed to reveal any detectable reduction in the cancer-associated death rate among the men who received a daily multivitamin tablet.

The rather breathlessly favorable media reaction to this study’s conclusions vividly illustrates how the superficial reporting of seemingly favorable clinical research findings can mislead the public into accepting overblown or invalid conclusions, such as those made by the authors of this particular research study.  As I discuss in A Cancer Prevention Guide for the Human Race, most of the published research in the area of cancer prevention research is of relatively low quality in terms of the methods used to conduct such research.  Moreover, as this particular prospective, randomized, placebo-controlled study shows, even clinical studies that actually utilize higher level methodologies still require both a careful and critical analysis of their findings and claims, and the conclusions of such studies should not be simply accepted at face value.  While this multivitamin study makes the very simple and straightforward claim that taking a commercial multivitamin and mineral supplement “significantly” reduces the incidence of cancer (at least among middle-aged and elderly male physicians), even a cursory evaluation of this study’s data and conclusions confirms that there is likely to be little or no overall health benefit, in terms of cancer risk and cancer-related death reduction, associated with taking a daily multivitamin and mineral supplement in otherwise healthy and well-nourished adults.  As the old saying goes, if something seems too good to true, it probably isn’t…..


A Cancer Prevention Guide for the Human Race is now available in both printed and digital formats from all major bookstores.  Get your copy now, and begin living an evidence-based cancer prevention lifestyle now!

 

Dr. Wascher’s latest video:

Dark as Night, Part 1

Dark as Night, Part 1

Dark as Night, Part 1



At this time, more than 8 percent of Americans are unemployed.  According to the Bureau of Labor Statistics, however, the unemployment rate for veterans who served on active duty between September 2001 and December 2011 is now more than 12 percent.  A new website, Veterans in Healthcare, seeks to connect veterans with potential employers.  If you are a veteran who works in the healthcare field, or if you are an employer who is looking for physicians, advanced practice professionals, nurses, corpsmen/medics, or other healthcare professionals, then please take a look at Veterans in Healthcare. As a retired veteran of the U.S. Army, I would also like to personally urge you to hire a veteran whenever possible.


For a groundbreaking overview of cancer risks, and evidence-based strategies to reduce your risk of developing cancer, order your copy of my bestselling book, “A Cancer Prevention Guide for the Human Race,” from AmazonBarnes & NobleBooks-A-MillionVroman’s Bookstore, and other fine bookstores!

Within one week of publication, A Cancer Prevention Guide for the Human Race was ranked #6 among all cancer-related books on the Amazon.com “Top 100 Bestseller’s List” for Kindle e-books. Within three months of publication, A Cancer Prevention Guide for the Human Race was the #1 book on the Amazon.comTop 100 New Book Releases in Cancer” list.




Disclaimer:  As always, my advice to readers is to seek the advice of your physician before making any significant changes in medications, diet, or level of physical activity


 

Dr. Wascher is an oncologic surgeon, professor of surgery, cancer researcher, oncology consultant, and a widely published author


 

I and the staff of Weekly Health Update would again like to take this opportunity to thank the more than 100,000 health-conscious people from around the world who visit this premier global health information website every month.  (More than 1.3 million pages of high-quality medical research findings were served to the worldwide audience of health-conscious people who visited Weekly Health Update in 2011!)  As always, we enjoy receiving your stimulating feedback and questions, and I will continue to try and personally answer as many of your inquiries as I possibly can.


 




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New Link to Diabetes, Cardiovascular Disease, Breast Cancer and Obesity in Women





 

A new study finds that high levels of the hormone neurotensin increase a woman’s risk of diabetes, cardiovascular disease, breast cancer, and possibly obesity as well.


 

NEW LINK TO DIABETES, CARDIOVASCULAR DISEASE, BREAST CANCER AND OBESITY IN WOMEN

As I discuss in my book, A Cancer Prevention Guide for the Human Race, both obesity and diabetes are associated with an increased risk of cancer.  Obesity, in particular, is a potent risk factor for breast cancer, and for recurrence of previously diagnosed breast cancer.  As I have noted recently, diabetes is also a known risk factor for breast cancer (Diabetes Significantly Increases Breast Cancer Risk).  Additionally, obesity is the single greatest risk factor for diabetes.

In view of the known associations between obesity, diabetes cardiovascular disease and cancer risk, a newly published prospective clinical research study from Sweden provides tantalizing evidence of at least one possible explanation for these associations.  In this study, 4,632 participants in the Malmö Diet and Cancer Study were followed between 1991 and 2009.  Upon entry into this prospective public health study, all participants underwent blood testing for proneurotensin, a precursor of the hormone neurotensin.  Neurotensin is most commonly found in the brain and the gastrointestinal tract, and its secretion is stimulated by food intake, and particularly by fat intake.  Neurotensin has many known physiological effects, including a reduction in appetite and food intake after meals.  Interestingly, neurotensin levels normally rise after consumption of a fatty meal, which is thought to result in a decreased appetite for more food, and reduced food intake.  However, in obese patients, neurotensin levels appear to actually decrease after consumption of a fatty meal, which suggests that an abnormal neurotensin response to food intake may play an important role in obesity.  Moreover, following obesity surgery, neurotensin levels have been observed to rise, in a normal fashion, following fatty meals.  Additionally, neurotensin has been observed to stimulate the growth of breast cancer tumors, while blocking neurotensin appears to reduce breast cancer tumor growth.  Finally, certain inherited variations of one of the receptors for neurotensin is known to increase the risk of cardiovascular disease, primarily by increasing levels of LDL cholesterol (the “bad” form of cholesterol).

The findings of this study were very intriguing.  Among patients with elevated levels of proneurotensin, diabetes was 28 percent more common, cardiovascular disease was 17 percent more common, and death due to cardiovascular disease was 29 percent more common.  Interestingly, the adverse health impact of high proneurotensin levels was significant only in women. Among women only, high levels of proneurotensin were associated with a 41 percent increase in the risk of diabetes, a 33 percent increase in the risk of cardiovascular disease, a 50 percent increase in the risk of death due to cardiovascular disease, a 44 percent increase in the risk of breast cancer, and a 13 percent overall increase in the risk of death due to any cause.

This study was published in the Journal of the American Medical Association.

While this study cannot explain the actual mechanism(s) whereby increased levels of proneurotensin and neurotensin may lead to an increased risk of diabetes, cardiovascular disease, and breast cancer in women, it nonetheless suggests that these hormones, when elevated, should be considered as markers for an increased risk of these serious illnesses, at least in women.  Moreover, based upon our knowledge of the physiological effects of neurotensin on digestion and appetite control, and its abnormal secretion in obese women, it is possible that stimulating an increase in neurotensin levels may help to restore more normal appetite levels, decrease caloric intake, and improve weight loss in obese patients.

More research needs to be done in order to understand how proneurotensin and neurotensin play a role in the development of obesity, diabetes, cardiovascular disease, and cancer.  In doing so, we may be able to open up exciting new opportunities to reduce the incidence and impact of these common causes of premature death, particularly among women.

 

A Cancer Prevention Guide for the Human Race is now available in both printed and digital formats from all major bookstores.  Get your copy now, and begin living an evidence-based cancer prevention lifestyle now!

 

Dr. Wascher’s latest video:

Dark as Night, Part 1


Dark as Night, Part 1

Dark as Night, Part 1



At this time, more than 8 percent of Americans are unemployed.  According to the Bureau of Labor Statistics, however, the unemployment rate for veterans who served on active duty between September 2001 and December 2011 is now more than 12 percent.  A new website, Veterans in Healthcare, seeks to connect veterans with potential employers.  If you are a veteran who works in the healthcare field, or if you are an employer who is looking for physicians, advanced practice professionals, nurses, corpsmen/medics, or other healthcare professionals, then please take a look at Veterans in Healthcare. As a retired veteran of the U.S. Army, I would also like to personally urge you to hire a veteran whenever possible.


For a groundbreaking overview of cancer risks, and evidence-based strategies to reduce your risk of developing cancer, order your copy of my bestselling book, “A Cancer Prevention Guide for the Human Race,” from AmazonBarnes & NobleBooks-A-MillionVroman’s Bookstore, and other fine bookstores!

Within one week of publication, A Cancer Prevention Guide for the Human Race was ranked #6 among all cancer-related books on the Amazon.com “Top 100 Bestseller’s List” for Kindle e-books. Within three months of publication, A Cancer Prevention Guide for the Human Race was the #1 book on the Amazon.comTop 100 New Book Releases in Cancer” list.




Disclaimer:  As always, my advice to readers is to seek the advice of your physician before making any significant changes in medications, diet, or level of physical activity


 

Dr. Wascher is an oncologic surgeon, professor of surgery, cancer researcher, oncology consultant, and a widely published author


 

I and the staff of Weekly Health Update would again like to take this opportunity to thank the more than 100,000 health-conscious people from around the world who visit this premier global health information website every month.  (More than 1.3 million pages of high-quality medical research findings were served to the worldwide audience of health-conscious people who visited Weekly Health Update in 2011!)  As always, we enjoy receiving your stimulating feedback and questions, and I will continue to try and personally answer as many of your inquiries as I possibly can.


 



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Viewing Photos of Kittens and Puppies Improves Attentiveness and Focus





 

A new study suggests that viewing pictures of cute baby animals improves our ability to perform focused tasks.


 

 

 

VIEWING PHOTOS OF KITTENS AND PUPPIES IMPROVES ATTENTIVENESS AND FOCUS

Most of the columns that I write for this blog deal with very serious health-related research studies.  This week, however, I will be discussing a somewhat more whimsical research study, compared to most of my prior columns.  This study from Japan appears in the current issue of the journal Public Library of Science (PLOS) One.

We all know that a young child, a kitten, or a puppy can evoke feelings of adoration and happiness.  Now, a newly published research study from Hiroshima, Japan, suggests that the positive feelings that arise when we see baby animals, or some other “cute thing,” may have a potentially greater impact on our behavior than has previously been appreciated.

In this innovative prospective study, several separate experiments were conducted using photos of cute little baby animals (kittens and puppies) and less cute adult animals (cats and dogs), as well as photos of “neutral” objects not associated with being “cute.”

In the first experiment, university student volunteers were asked to perform a task requiring significant manual dexterity after viewing photos of, variously, cute baby animals and (not so cute) adult animals.  In this experiment, viewing photos of cute baby animals increased the successful performance of the assigned task by 44 percent, as compared to only a 12 percent improvement in performance among the students who performed the same task after viewing photos of adult animals.

In the second experiment, the participating college students were asked to perform a visual search task after looking at the cute and not so cute animal photos.  Once again, task-related performance significantly improved after looking at the pictures of kittens and puppies (16 percent), compared to the degree of improvement that was noted after viewing photos of adult cats and dogs (1 percent).

When the researchers analyzed the data from this study, they determined that looking at photos of cute little kittens and puppies significantly improved attentiveness to focused tasks such as those performed in this study.  Based upon the findings of this study and previous similar research studies, the authors of this study propose that a “cuteness-triggered positive emotion” is associated with increased motivation to complete assigned tasks, as well as improved processing of information associated with performing manual and visual tasks (as was demonstrated in this new research study).  They further suggest that intentional exposure to “cute objects” might be helpful in stimulating positive behaviors in both the workplace and at home, particularly when tasks requiring careful attention are being performed.

kitten-puppy-photo

 

A Cancer Prevention Guide for the Human Race is now available in both printed and digital formats from all major bookstores.  Get your copy now, and begin living an evidence-based cancer prevention lifestyle now!

 

Dr. Wascher’s latest video:

Dark as Night, Part 1


Dark as Night, Part 1

Dark as Night, Part 1



At this time, more than 8 percent of Americans are unemployed.  According to the Bureau of Labor Statistics, however, the unemployment rate for veterans who served on active duty between September 2001 and December 2011 is now more than 12 percent.  A new website, Veterans in Healthcare, seeks to connect veterans with potential employers.  If you are a veteran who works in the healthcare field, or if you are an employer who is looking for physicians, advanced practice professionals, nurses, corpsmen/medics, or other healthcare professionals, then please take a look at Veterans in Healthcare. As a retired veteran of the U.S. Army, I would also like to personally urge you to hire a veteran whenever possible.


For a groundbreaking overview of cancer risks, and evidence-based strategies to reduce your risk of developing cancer, order your copy of my bestselling book, “A Cancer Prevention Guide for the Human Race,” from AmazonBarnes & NobleBooks-A-MillionVroman’s Bookstore, and other fine bookstores!

Within one week of publication, A Cancer Prevention Guide for the Human Race was ranked #6 among all cancer-related books on the Amazon.com “Top 100 Bestseller’s List” for Kindle e-books. Within three months of publication, A Cancer Prevention Guide for the Human Race was the #1 book on the Amazon.comTop 100 New Book Releases in Cancer” list.




Disclaimer:  As always, my advice to readers is to seek the advice of your physician before making any significant changes in medications, diet, or level of physical activity


 

Dr. Wascher is an oncologic surgeon, professor of surgery, cancer researcher, oncology consultant, and a widely published author


 

I and the staff of Weekly Health Update would again like to take this opportunity to thank the more than 100,000 health-conscious people from around the world who visit this premier global health information website every month.  (More than 1.3 million pages of high-quality medical research findings were served to the worldwide audience of health-conscious people who visited Weekly Health Update in 2011!)  As always, we enjoy receiving your stimulating feedback and questions, and I will continue to try and personally answer as many of your inquiries as I possibly can.


 






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