High Fat Diet Decreases Metabolism and Increases Anger and Hostility



A new study finds that saturated fat decreases metabolism and physical activity, and increases anger and hostility.


 

HIGH FAT DIET DECREASES METABOLISM AND INCREASES ANGER AND HOSTILITY

As I have written about extensively in my bestselling book, A Cancer Prevention Guide for the Human Race, a diet low in saturated fat and meat products, such as the Mediterranean diet, has been linked to a decreased risk of cancer (and cardiovascular disease) when compared to the traditional Western diet, which is rich in saturated fat and meat. Now, a new study has linked a Mediterranean-type diet, low in saturated fat, to other potential health benefits, including greater levels of physical activity, a higher metabolic rate, and, somewhat surprisingly, less angry and hostile moods. This study appears in the current issue of the American Journal of Clinical Nutrition.

In this prospective randomized clinical study, 32 young adults were separated into two groups. The first group used cooking oils high in saturated fat, while the second group used cooking oils low in saturated fat and high in monounsaturated fat. After three weeks, both groups were “crossed over,” and had their cooking oils switched for an additional three weeks. (This clinical study’s “crossover” design is a powerful means of eliminating potential biases that can lead to false conclusions.) Another important aspect of this study was that all food consumed by the study’s volunteer research subjects was provided (and controlled) by the researchers. Moreover, the food provided to both groups of study volunteers was the same, and only the cooking oil differed between the two study groups.

All research volunteers were continuously assessed with regards to physical activity levels and resting metabolic rates (“resting energy expenditure”). Due to the observed differences in physical activity levels between the two groups of volunteers, the researchers also subjected study volunteers to a validated mood assessment questionnaire, to see if differences in mood might account for the significantly different levels of physical activity between the two groups of research volunteers.

The results of this intriguing prospective randomized clinical study were quite interesting. Firstly, continuous measurements of physical activity showed that the monounsaturated oil (Mediterranean-like diet) group was 12 percent more active, physically, than the saturated fat group (Western-type diet). Secondly, the resting metabolic rate of the monounsaturated oil group was almost 5 percent higher than that of the saturated fat cooking oil group, suggesting that the young adults who were consuming primarily monounsaturated fat were burning more calories at rest than the group that was using saturated fat. Finally, the monounsaturated fat group scored significantly lower on the anger-hostility scale of the mood assessment questionnaire than the volunteers who were using cooking oil containing saturated fat.

To summarize, this innovative prospective clinical research study found that a Mediterranean-like diet, low in saturated fat, was associated with increased levels of physical activity, a higher resting metabolism rate, and less anger and hostility, when compared to a Western-like diet that was rich in saturated fat. These findings add further evidence to the data that I extensively discuss in A Cancer Prevention Guide for the Human Race, showing that a Mediterranean diet low in saturated fat and meat products, and high in unsaturated oils, whole grains, fresh fruit and vegetable, fish, and poultry, is an important strategy for good health.

For a groundbreaking overview of cancer risks, and evidence-based strategies to reduce your risk of developing cancer, order your copy of my bestselling book, “A Cancer Prevention Guide for the Human Race,” from AmazonBarnes & Noble, Books-A-Million, Vroman’s Bookstore, and other fine bookstores!

Within one week of publication, A Cancer Prevention Guide for the Human Race was ranked #6 among all cancer-related books on the Amazon.com “Top 100 Bestseller’s List” for Kindle e-books. Within three months of publication, A Cancer Prevention Guide for the Human Race was the #1 book on the Amazon.com Top 100 New Book Releases in Cancer” list.

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Dr. Wascher’s latest video:

Dark as Night, Part 1

Dark as Night, Part 1

Dark as Night, Part 1

At this time, more than 8 percent of Americans are unemployed.  According to the Bureau of Labor Statistics, however, the unemployment rate for veterans who served on active duty between September 2001 and December 2011 is more than 12 percent.  A new website, Veterans in Healthcare, seeks to connect veterans with potential employers.  If you are a veteran who works in the healthcare field, or if you are an employer who is looking for physicians, advanced practice professionals, nurses, corpsmen/medics, or other healthcare professionals, then please take a look at Veterans in Healthcare. As a retired veteran of the U.S. Army, I would also like to personally urge you to hire a veteran whenever possible.


Disclaimer:  As always, my advice to readers is to seek the advice of your physician before making any significant changes in medications, diet, or level of physical activity


Dr. Wascher is an oncologic surgeon, professor of surgery, cancer researcher, oncology consultant, and a widely published author


 

I and the staff of Weekly Health Update would again like to take this opportunity to thank the more than 100,000 health-conscious people from around the world who visit this premier global health information website every month.  Over the past 12 months, more than 2.8 million pages of high-quality medical research findings were served to the worldwide audience of health-conscious readers.  As always, we enjoy receiving your stimulating feedback and questions, and I will continue to try and personally answer as many of your inquiries as I possibly can.


 


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American Surgeons in Crisis: Implications for Healthcare






 

A new study finds that more than half of surgeons are experiencing work-home conflicts that threaten their personal and professional wellbeing.


 

AMERICAN SURGEONS IN CRISIS:  IMPLICATIONS FOR HEALTHCARE

As I have discussed in previous columns (The Silent Epidemic of Surgeon Burnout and DepressionEpidemic of Alcohol Abuse Among Surgeons), there are quiet and evolving, and disturbing, developments within the community of American surgeons, and these developments may portend of significant potential future problems for surgeons, and for patients who require surgical care.  Now, a newly published research study, which appears in the current issue of the Archives of Surgery, further suggests that the epidemic of surgeon burnout and depression is indeed real, and has serious potential implications for both surgeons and their patients.

In this study, 7,197 active surgeons were surveyed, electronically, by the American College of Surgeons, using questions from validated surveys that assess for career burnout, depression, quality of life, alcohol use, and other measures of satisfaction with both personal and professional life attributes.

When asked if they had experienced any significant conflicts between their “work lives” and their “home lives” within the previous three weeks, an astounding 53 percent of the queried surgeons replied, “Yes.”  Thus, more than half of all surgeons who participated in this confidential survey reported substantial and distressing conflicts between their professional lives and their home lives within the preceding three weeks.

When the study’s authors analyzed the personal and professional factors that were most closely associated with “work-home conflicts,” and with both personal and professional dissatisfaction, a clearer picture emerged.  For example, the number of hours worked per week, having children, the surgeon’s gender, and the type of surgical practice were all closely linked with work-home conflicts, and with lower levels of personal and professional satisfaction.  For example, surgeons who practiced at Veterans Administration hospitals were 91 percent more likely to report work-home conflicts when compared to surgeons in private practice, while surgeons who practiced at an academic medical center were 19 percent more likely to report such conflicts when compared to private practice surgeons.  Not surprisingly, having children at home was associated with a 65 percent greater likelihood of work-home conflict when compared to surgeons without children at home.  Working more hours per week and being younger were also factors associated with a higher likelihood of work-home conflict, as was being a female surgeon (i.e., when compared to male surgeons).  Surgeon specialty was also significantly linked to work-home conflicts and overall lower satisfaction levels, with broadly practicing general surgeons being twice as likely to report work-home conflicts as surgeons in other specialties (e.g., breast surgeons, heart surgeons, neurosurgeons, and other subspecialist surgeons).

The high level of work-home conflicts identified among surgeons is an issue of great concern to all of us, as such conflicts were significantly associated with career burnout, exhaustion, decreased quality of life, depression, relationship difficulties, alcohol abuse, and overall career dissatisfaction by scientifically validated surveys.  Surgeons reporting recent work-home conflicts were also substantially less likely to recommend surgery as a career option to their children.

In addition to higher levels of burnout, depression, alcohol abuse, relationship difficulties, and career dissatisfaction, surgeons who reported recent work-home conflicts were also 77 percent more likely to be planning to reduce their clinical work hours, and71 percent more likely to be planning to leave their surgical practices for reasons other than planned retirement.

At a time when the demand for some types of surgical care is already outstripping the supply of experienced, competent surgeons in many areas of the country, the findings of this study are cause for considerable concern.  For example, looking into the near future, our population is aging, and many acute and chronic diseases that require surgical treatment are more common in elderly patients.  Therefore, there is real concern that an increasingly burned-out surgeon workforce, and a declining interest in the more challenging surgical specialties (like general surgery) by today’s medical students, will someday soon leave the United States with an inadequate number of experienced surgeons to meet our nation’s healthcare needs.

All of the above noted adverse factors within the American surgeon community, once again, raise the concern that adequate levels of surgical care may not be available in the not too distant future if significant changes in surgical training and surgical practice are not considered and implemented, particularly in the workhorse specialty of general surgery.  The surgical community has been, admittedly, slow to appreciate or embrace generational changes in perceptions about work-life balance, and has only grudgingly (and recently) acquiesced to external pressures to treat its surgeons-in-training in a more considerate and supportive manner, compared to the conditions that surgery interns and residents toiled under during my era of training, as well as previous generations of surgical trainees.  (When I was a surgical intern, in the late 1980s, there were no limitations on the number of hours that interns and residents were expected to work in the hospital, including the number of nights spent on call for emergencies within the hospital, and it was not uncommon for us to spend 100 to 120 hours inside the hospital each and every week.)  Regardless of how more senior surgeons feel about it, it must be acknowledged that the current generation of medical students and young surgeons, both male and female, are much more concerned about work-life balance, and overall quality of life issues, than was typical for my generation of surgeons.

On a brighter note, the American College of Surgeons’ sponsorship of this research study, and others like it, suggests that the older generation of surgeons who currently serve as senior leaders and mentors for young surgeons and surgical trainees may, finally, be coming to grips with the rather dramatic shift in attitudes and priorities among their young charges. Hopefully, it is not too late to make meaningful structural changes in surgical training and surgical practice conditions before there are widespread adverse public health consequences to the ongoing crisis among the community of surgeons in the United States….

 

A Cancer Prevention Guide for the Human Race is now available in both printed and digital formats from all major bookstores.  Get your copy now, and begin living an evidence-based cancer prevention lifestyle!


Dr. Wascher’s latest video:

Dark as Night, Part 1


Dark as Night, Part 1

Dark as Night, Part 1


At this time, more than 8 percent of Americans are unemployed.  According to the Bureau of Labor Statistics, however, the unemployment rate for veterans who served on active duty between September 2001 and December 2011 is now more than 12 percent.  A new website, Veterans in Healthcare, seeks to connect veterans with potential employers.  If you are a veteran who works in the healthcare field, or if you are an employer who is looking for physicians, advanced practice professionals, nurses, corpsmen/medics, or other healthcare professionals, then please take a look at Veterans in Healthcare. As a retired veteran of the U.S. Army, I would also like to personally urge you to hire a veteran whenever possible.


For a groundbreaking overview of cancer risks, and evidence-based strategies to reduce your risk of developing cancer, order your copy of my bestselling book, “A Cancer Prevention Guide for the Human Race,” from AmazonBarnes & NobleBooks-A-MillionVroman’s Bookstore, and other fine bookstores!

Within one week of publication, A Cancer Prevention Guide for the Human Race was ranked #6 among all cancer-related books on the Amazon.com “Top 100 Bestseller’s List” for Kindle e-books. Within three months of publication, A Cancer Prevention Guide for the Human Race was the #1 book on the Amazon.comTop 100 New Book Releases in Cancer” list.




Disclaimer:  As always, my advice to readers is to seek the advice of your physician before making any significant changes in medications, diet, or level of physical activity


 

Dr. Wascher is an oncologic surgeon, professor of surgery, cancer researcher, oncology consultant, and a widely published author


 

I and the staff of Weekly Health Update would again like to take this opportunity to thank the more than 100,000 health-conscious people from around the world who visit this premier global health information website every month.  (More than 1.3 million pages of high-quality medical research findings were served to the worldwide audience of health-conscious people who visited Weekly Health Update in 2011!)  As always, we enjoy receiving your stimulating feedback and questions, and I will continue to try and personally answer as many of your inquiries as I possibly can.


 





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Depression After Childhood Abuse May Be Linked To A Specific Gene







 

A new study suggests that a variant of a recently discovered gene may double the risk of lifelong depression after childhood abuse.


 

 

CHRONIC DEPRESSION AFTER CHILDHOOD ABUSE MAY BE LINKED TO A NEW GENE

The age-old debate about “nature versus nurture” has become increasingly complicated as we continue to learn more about the impact of individual genes on our risk for various illnesses.  While it has become widely accepted that specific genetic patterns may predispose some of us to a very high risk of certain physical illnesses, such as cancer and cardiovascular disease, the potential linkage between specific genes and the risk of mental illness has been less clear.  At the same time, however, it has long been known that some mental health disorders, including depression, anxiety disorder, panic disorder, bipolar disorder, and schizophrenia, tend to run in families, which suggests that there may be at least some genetic component to these illnesses.

Over the past 5 years, fundamental new research has begun to suggest that certain genes may indeed be associated with an increased risk of specific mental illnesses.  However, most mental health experts believe that having a specific form of a gene linked to mental illness does not, by itself, mean that an affected individual faces a 100 percent risk of developing a mental illness.  Getting back to that “nature versus nurture” debate once again, it appears that having a genetic variant associated with a specific mental health illness probably predisposes an affected person to develop that particular mental health disorder, but does not guarantee that this will happen.  More specifically, an individual person’s experiences and environment during early life (i.e., the “nurture”) appear to have a significant impact on whether or not genes associated with an increased risk of mental illness (i.e., the “nature”) will actually lead to the development of mental illness.

Now, a newly published clinical study provides strong evidence that a specific form of a single gene can significantly increase the likelihood of major depression in adults following physical abuse during childhood, while another variant of this same gene appears to decrease the risk of chronic depression in similarly abused adults.  This intriguing research study appears in the current issue of the Archives of General Psychiatry.

This new research study was inspired by previous research with laboratory animals that identified a network of neurons in the brain that use chemicals called endocannabinoids to communicate with each other.  (If the word “endocannabinoid” sounds vaguely familiar, it is because these naturally occurring neurotransmitters in the brain also have counterparts in the plant world, most notably in cannabis, or marijuana, plants!)  Previous research has also suggested that the endocannabinoid system in the brain may play an important role in adaptation to stress, including the moderation of our mood following stressful events.

In this new study, two groups of patient-volunteers were included.  The first group consisted of 1,041 young adult female twins in the United States, while the second group consisted of 1,428 Australian adults known to be addicted to heroin. (An additional 506 Australian volunteers without heroin addiction participated in this study as the control group for the heroin-addicted volunteers.)  The presence of depression, and in particular, depression with anhedonia (a term that indicates the inability to enjoy experiences that most of us find pleasurable), was assessed among all of these patient-volunteers.  The absence or presence of a history of physical abuse, by a parent or caregiver, during childhood was also evaluated.  Testing of the gene which codes for the human endocannabinoid receptor in the brain was performed on all of these research volunteers, as well.

The findings of this study were highly significant.  Not surprisingly, the study volunteers who reported having experienced significant childhood physical abuse had a much higher incidence of depression when compared to those volunteers who did not experience physical abuse as children.  Among the volunteers who had experienced significant physical abuse during childhood, a single, specific variant of the endocannabinoid receptor gene appeared to be highly protective against anhedonic depression when compared to volunteers who possessed the more common variant of this gene.  Specifically, only 29 percent of abused volunteers with this less common variant of the endocannabinoid receptor gene experienced anhedonic symptoms, while 57 percent of the previously abused volunteers with the most common form of this same gene were found to have symptoms of anhedonic depression.

The findings of this study strongly suggest that certain naturally occurring variants of specific genes may either increase or decrease the risk of mental illness (and in the case of this clinical study, major depression with anhedonia) following stressful experiences earlier in life.  Not only do this study’s findings suggest a method of screening patients who might be at significantly increased risk for major depression following stressful events in their early lives, but the linkage of a specific gene within the brain’s endocannabinoid system with depression following traumatic childhood experiences may someday allow for a more effective treatment for post-traumatic major depression, using medications targeted at the specific genetic variation that leads to this increased risk of depression following childhood trauma.


At this time, more than 8 percent of Americans are unemployed.  According to the Bureau of Labor Statistics, however, the unemployment rate for veterans who served on active duty between September 2001 and December 2011 is now more than 12 percent.  A new website, Veterans in Healthcare, seeks to connect veterans with potential employers.  If you are a veteran who works in the healthcare field, or if you are an employer who is looking for physicians, advanced practice professionals, nurses, corpsmen/medics, or other healthcare professionals, then please take a look at Veterans in Healthcare. As a retired veteran of the U.S. Army, I would also like to personally urge you to hire a veteran whenever possible.

 

For a groundbreaking overview of cancer risks, and evidence-based strategies to reduce your risk of developing cancer, order your copy of my bestselling book, “A Cancer Prevention Guide for the Human Race,” from AmazonBarnes & NobleBooks-A-MillionVroman’s Bookstore, and other fine bookstores!

Within one week of publication, A Cancer Prevention Guide for the Human Race was ranked #6 among all cancer-related books on the Amazon.com “Top 100 Bestseller’s List” for Kindle e-books. Within three months of publication, A Cancer Prevention Guide for the Human Race was the #1 book on the Amazon.comTop 100 New Book Releases in Cancer” list.




Disclaimer:  As always, my advice to readers is to seek the advice of your physician before making any significant changes in medications, diet, or level of physical activity


 

Dr. Wascher is an oncologic surgeon, professor of surgery, cancer researcher, oncology consultant, and a widely published author


 

I and the staff of Weekly Health Update would again like to take this opportunity to thank the more than 100,000 health-conscious people from around the world who visit this premier global health information website every month.  (More than 1.3 million pages of high-quality medical research findings were served to the worldwide audience of health-conscious people who visited Weekly Health Update in 2011!)  As always, we enjoy receiving your stimulating feedback and questions, and I will continue to try and personally answer as many of your inquiries as I possibly can.


 











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