European Ash Seed Extract (FraxiPure™) Decreases Obesity and Blood Glucose

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Previous studies have suggested that an extract of seeds from the European Ash tree (Fraxinus excelsior) may reduce weight gain, and may decrease the rise in blood sugar levels that accompanies meals. A newly published laboratory study, which appears in the current issue of the journal Phytomedicine, appears to add further weight to these hypotheses.

In this laboratory study, a commercially available extract of European Ash tree seeds, FraxiPure™, was included in the diet of mice that were intentionally fed a high-fat diet over a period of 16 weeks. Two additional groups of mice were used as “controls,” including mice fed either a low-fat diet or a high-fat diet (but without the addition of FraxiPure™).

Among the mice receiving both a high-fat diet and FraxiPure™, the weight gain associated with a high-fat diet was 32 percent lower than the weight gain that was observed in the mice that received a high-fat diet without FraxiPure™. Fasting blood sugar (glucose) levels were also reduced by a highly significant 77 percent among the mice that received the FraxiPure™ supplement. Insulin levels in the blood were also decreased by 53 percent among the mice that received the FraxiPure™ dietary supplement. Another interesting apparent benefit of FraxiPure™ was a 67 percent decrease in the incidence of fatty liver changes, which often accompanies high-fat diets, obesity, and diabetes in humans, and which has been linked with potentially severe liver disease in humans.

It is too soon to tell if the many apparent health benefits of FraxiPure™ that were observed in these laboratory mice will also apply equally to humans. (Unfortunately, what works in laboratory mice and rats often does not work in humans.) However, in view of the worldwide epidemic of obesity, and the many serious ailments that are linked to obesity (including cardiovascular disease, diabetes, lung disease, cancer, chronic liver disease, arthritis, and gallstones, to name a few), a prospective, randomized, placebo-controlled clinical research trial should now be considered, to assess both the effectiveness and the safety of FraxiPure™ (or other European Ash seed extracts) in humans.

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Disclaimer: As always, my advice to readers is to seek the advice of your physician before making any significant changes in medications, diet, or level of physical activity

Dr. Wascher is an oncologic surgeon, a professor of surgery, a cancer researcher, an oncology consultant, and a widely published author

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