Common Household Chemical May Double Heart Disease Risk





 

A new clinical study finds that a common household chemical (perfluorooctanoic acid) may double the risk of heart disease.


 

 

COMMON HOUSEHOLD CHEMICAL MAY DOUBLE HEART DISEASE RISK

Cardiovascular disease continues to be one of the most common causes of disability and death, accounting for one out of every four deaths in the United States.  The most common risk factors for cardiovascular disease are well known, and include lack of physical activity, obesity, high blood pressure, smoking, elevated cholesterol, and diabetes.  Additionally, a strong family history of cardiovascular disease, particularly at an early age, also increases one’s risk of cardiovascular disease.  Now, a newly published research study raises the possibility that a manmade chemical commonly found in household products may also significantly increase the risk of cardiovascular disease.  This new study appears in the current issue of the Archives of Internal Medicine.

Perfluorooctanoic acid (PFOA) appears in numerous household products, including carpet-care products, clothing, floor-care products, non-stick surfaces in cookware and paper food-wrapping products, polishes, dental floss, and implantable medical devices, among others.  In fact, PFOA is so ubiquitous in the United States that it is detectable in the blood of 98 percent of the population.  Moreover, once ingested, PFOA remains in the human body for many years, and can therefore accumulate at increasingly higher levels over time.

In addition to being a known carcinogen, PFOA has been previously linked with cardiovascular disease in animal studies.  Therefore, this new clinical study was designed to assess the association between cardiovascular disease and blood levels of PFOA in humans.  In this clinical study, 1,216 volunteers were recruited from the ongoing National Health and Nutritional Examination Survey (NHANES) prospective public health study, and were tested for the level of PFOA in their blood.  They also underwent both extensive surveys regarding their health and physical examinations for signs of peripheral arterial disease.  Importantly, known risk factors for cardiovascular and peripheral artery disease were assessed in each of these volunteers, and this information was used to improve the accuracy of the study’s conclusions regarding PFOA and the risk of cardiovascular and peripheral arterial disease.

Even after correcting for preexisting risk factors for cardiovascular and peripheral arterial disease, this study found a significant association between PFOA levels in the blood and the incidence of cardiovascular disease and peripheral arterial disease.  When comparing volunteers with the lowest and highest levels of PFOA, patients with the highest levels of POFA were found to have two times the risk of developing cardiovascular disease and almost twice the risk of developing peripheral arterial disease.  Once again, the association between PFOA levels in the blood and the risk of cardiovascular and peripheral arterial disease remained even after correcting for gender, age, race/ethnicity, smoking status, obesity, diabetes, high blood pressure and elevated cholesterol levels.

While the findings of this study will have to be verified by additional and larger prospective clinical studies, these findings do nonetheless raise concerns that PFOA may, itself, be an independent cause of cardiovascular and peripheral vascular disease.  Given that almost every adult in the United States has at least some measurable concentration of PFOA in their blood, even a small associated increase in the risk of cardiovascular and peripheral vascular disease could have a significant impact on the overall incidence of these diseases within the larger population.  According to the Centers for Disease Control (CDC), approximately 40 percent of adult Americans already have at least two conventional cardiovascular disease risk factors.  However, given that PFOA is present in virtually everyone’s body, our risk of cardiovascular and peripheral artery disease may actually be significantly higher than previously appreciated, based upon the findings of this important new clinical study.

 

At this time, more than 8 percent of Americans are unemployed.  According to the Bureau of Labor Statistics, however, the unemployment rate for veterans who served on active duty between September 2001 and December 2011 is now more than 12 percent.  A new website, Veterans in Healthcare, seeks to connect veterans with potential employers.  If you are a veteran who works in the healthcare field, or if you are an employer who is looking for physicians, advanced practice professionals, nurses, corpsmen/medics, or other healthcare professionals, then please take a look at Veterans in Healthcare. As a retired veteran of the U.S. Army, I would also like to personally urge you to hire a veteran whenever possible.


For a groundbreaking overview of cancer risks, and evidence-based strategies to reduce your risk of developing cancer, order your copy of my bestselling book, “A Cancer Prevention Guide for the Human Race,” from AmazonBarnes & NobleBooks-A-MillionVroman’s Bookstore, and other fine bookstores!

Within one week of publication, A Cancer Prevention Guide for the Human Race was ranked #6 among all cancer-related books on the Amazon.com “Top 100 Bestseller’s List” for Kindle e-books. Within three months of publication, A Cancer Prevention Guide for the Human Race was the #1 book on the Amazon.comTop 100 New Book Releases in Cancer” list.




Disclaimer:  As always, my advice to readers is to seek the advice of your physician before making any significant changes in medications, diet, or level of physical activity


 

Dr. Wascher is an oncologic surgeon, professor of surgery, cancer researcher, oncology consultant, and a widely published author


 

I and the staff of Weekly Health Update would again like to take this opportunity to thank the more than 100,000 health-conscious people from around the world who visit this premier global health information website every month.  (More than 1.3 million pages of high-quality medical research findings were served to the worldwide audience of health-conscious people who visited Weekly Health Update in 2011!)  As always, we enjoy receiving your stimulating feedback and questions, and I will continue to try and personally answer as many of your inquiries as I possibly can.


 






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Lifestyle, Diet and Diabetes Risk

Welcome to Weekly Health Update


New research reveals the profound impact of diet, obesity, and lifestyle factors on diabetes risk.



 

 

LIFESTYLE, DIET AND DIABETES RISK

Along with the incidence of obesity, the incidence of diabetes has recently skyrocketed in the United States and around the world.  The list of health complications associated with diabetes is frightening, and includes heart disease, peripheral vascular disease, stroke, kidney failure, progressive blindness, and as I discuss in my book, A Cancer Prevention Guide for the Human Race, an increased risk of cancer.

Now, a newly published clinical research study, which included more than 200,000 adult volunteers, sheds important light on the major lifestyle-associated risk factors for this life-threatening disease.  Nearly 2 million adults will be newly diagnosed with diabetes this year in the United States, and nearly 80 million Americans are currently living with diabetes at this time. In fact, diabetes has become such a serious public health problem that it is now considered the seventh leading cause of death in the United States!

This newly published prospective public health study appears in the current issue of the Annals of Internal Medicine, and was sponsored by the National Heart, Lung, and Blood Institute and the National Cancer Institute, as part of the National Institutes of Health-AARP Diet and Health Study.

A total of 114, 996 men and 92,483 women, aged 50 to 71 years, participated in this public health study; and this huge group of research volunteers was closely followed for an average of 10 years. Importantly, none of these research volunteers had diabetes, heart disease, or cancer at the time they initially joined this research study.

After evaluating diet, level of physical activity, smoking status, and alcohol intake, this enormous group of research volunteers was assessed for the risk of onset of diabetes according to these lifestyle factors. Altogether, about 10 percent of the men and 8 percent of the women went on to develop diabetes during the 10-year course of this public health study. When compared to men who ate poorly and did not exercise, and who also smoked and regularly consumed alcohol, the men who had very healthy behaviors in these same areas had a 39 percent lower risk of developing diabetes, while the women with healthy lifestyle behaviors experienced a 57 percent lower risk of diabetes when compared to the women with unhealthy lifestyle behaviors. Even more impressive was the additive role of obesity on diabetes risk. When all of the previously mentioned healthy lifestyle behaviors were combined with the absence of being overweight or obese, men experienced a whopping 72 percent decrease in the risk of diabetes, while women experienced an extraordinary 84 percent reduction in the risk of developing diabetes. Importantly, these dramatic reductions in the risk of diabetes were maintained even among the men and women who had a family history of diabetes or obesity.

This huge prospective public health study adds important and helpful information to our understanding regarding the most important risk factors for diabetes, and reveals just how important eating a healthy diet, maintaining a healthy weight, getting regular exercise, abstaining from tobacco use, and minimizing alcohol intake are to the prevention of diabetes.  Other large public health studies have also conclusively linked these healthy lifestyle-associated behaviors with a significant reduction in the risk of cardiovascular disease (including heart disease, peripheral vascular disease, and stroke) and cancer, as well!




For a comprehensive guide to living an evidence-based cancer prevention lifestyle, order your copy of my new book, A Cancer Prevention Guide for the Human Race.  For the price of a cheeseburger, fries, and a shake, you can purchase this landmark new book, in both paperback and e-book formats, and begin living an evidence-based cancer prevention lifestyle today!

For a groundbreaking overview of cancer risks, and evidence-based strategies to reduce your risk of developing cancer, order your copy of my new book, A Cancer Prevention Guide for the Human Race,” from Amazon, Barnes & Noble, Books-A-Million,Vroman’s Bookstore, and other fine bookstores!

On Thanksgiving Day, 2010, A Cancer Prevention Guide for the Human Race was ranked #6 among all cancer-related books on the Amazon.com “Top 100 Bestseller’s List” for Kindle e-books! On Christmas Day, 2010, A Cancer Prevention Guide for the Human Race was the #1 book on the Amazon.comTop 100 New Book Releases in Cancer” list!


Disclaimer:  As always, my advice to readers is to seek the advice of your physician before making any significant changes in medications, diet, or level of physical activity


Dr. Wascher is an oncologic surgeon, professor of surgery, cancer researcher, oncology consultant, and a widely published author


For a different perspective on Dr. Wascher, please click on the following YouTube link:

Texas Blues Jam


I and the staff of Weekly Health Update would again like to take this opportunity to thank the more than 100,000 health-conscious people, from around the world, who visit this premier global health information website every month. (More than 1.2 million health-conscious people visited Weekly Health Update in 2010!) As always, we enjoy receiving your stimulating feedback and questions, and I will continue to try and personally answer as many of your inquiries as I possibly can.





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